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The U1 Adaptor technology is a new way to silence gene expression, an advance that could hold promise for disease treatment.
Combining U1 Adaptors and RNA interference reduced gene expression further, suggesting a dual approach could
allow these molecular therapies to work at lower doses.
Unlike other gene silencing technologies, U1 Adaptor molecules do not require enzymatic activity to exert their effect.
This means U1 Adaptors can be highly modified allowing for more flexible design to promote both specialized delivery
to the target cells and increased stability thereby lowering the therapeutic dose.
U1 Adaptors can be used when other gene silencing methods are not sufficiently effective or have side-effects that need
to be avoided.